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Review Open access Sep 2026

Preclinical Evidence and Mechanisms of Traditional Chinese Medicine Polysaccharides Regulating the Gut–Lung Axis via Gut Microbiota in Respiratory Diseases

Traditional Chinese medicine (TCM) polysaccharides are important active components of traditional Chinese medicine, and their anti-inflammatory, immunomodulatory, and mucosal barrier protective effects have attracted widespread attention. Since most traditional Chinese medicine polysaccharides are difficult to be compl...

Xin-Qian Rong, Xiao-Meng Zhang, Cheng Lu et al. · 0 citations
Review Open access Sep 2026

Plant-Derived Natural Product Nanodelivery System in Cancer Therapy.

This review provides a comprehensive framework for the rational development of plant-derived natural product nanomedicines in precision oncology with a focus on three major strategies: chemical conjugation, self-assembly of natural products, and codelivery of natural products with chemotherapeutic agents.

Chang-Qi Shi, Lu-Lu Zhang, Lan Yan et al. · 0 citations
Review Open access Aug 2026

Gut Microbial Functional Ecology and Microbiota-Derived Metabolites in Rheumatoid Arthritis Autoimmunity

This review follows the framework of “anti-inflammatory/pro-inflammatory microbial niches—microbiota-derived metabolites—immune cell homing and migration” to summarize recent advances in the role of gut microbiota and their derivatives in RA onset, progression, and therapeutic response.

Xin-Qian Rong, Xiao-Meng Zhang, Yong Tan et al. · 2 citations
Open access Aug 2026

Identification and Validation of ISG20 as a Shared Immune-Related Crosstalk Marker in Rheumatoid Arthritis and Inflammatory Bowel Disease

ISG20 serves as a crosstalk molecular link across the RA and IBD, providing molecular landscape for shared pathogenesis and diagnostic window for patients predisposed to the RA-IBD co-occurrence clinical phenotype.

Lan Yan, Chang-Qi Shi, Shuaipeng Yuan et al. · 0 citations

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