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Author

Cheng-Jie Xu

2 papers indexed here

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Open access Sep 2026

Baseline mood and non-motor symptom burden are associated with cognitive progression in Parkinson’s disease: an interpretable follow-up cohort analysis with separate neuroimaging, molecular, and digital analyses in independent samples

Clinically useful artificial intelligence and machine-learning studies in healthcare require interpretable features, internal validation, and explicit boundaries between primary inference and external context. Among 1,612 baseline Parkinson’s Progression Markers Initiative (PPMI) participants, 1,439 had evaluable post-...

Jiang-Bin Ren, Jiang-Hao Ren, Hao-Heng Yu et al. · 0 citations
Open access Oct 2026

scTIME: single-cell-informed interpretable modeling of immunotherapy-associated immune states in non-small cell lung cancer

Immune checkpoint inhibitor response in non-small cell lung cancer (NSCLC) reflects coordinated tumor and immune states that are not fully captured by single biomarkers. We developed scTIME, an interpretable model that translates single-cell immune programs into bulk transcriptomic scores, and integrated public single-...

Guo-Zhi Chen, Chen-Qiu You, H.-O. Gao et al. · 0 citations

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