A Lactose-Selective α1,3-Fucosyltransferase from Akkermansia muciniphila Expands the Biosynthetic Toolkit for Fucosylated Human Milk Oligosaccharides
Fucosylated human milk oligosaccharides (HMOs) are important bioactive glycans, but their biosynthetic production requires fucosyltransferases with predictable acceptor selectivity to avoid regioisomer formation and downstream purification burdens. Here we identify an α1,3-fucosyltransferase from Akkermansia muciniph...