Open access
Sep 2026
MAP2-mediated integrin dysregulation reprograms cancer cell plasticity in hepatocellular carcinoma
Targeting tumor cell plasticity is central to overcome drug resistance and metastasis. Through lineage-tracing and lineage-ablation studies, our team has previously shown hepatocellular carcinoma (HCC) cells marked by CD133 to represent a functional subset displaying dedifferentiated status with stemness traits, yet th...
U. Lou, Tin-Lok Wong, I. B. Huang et al.
· Nature Communications · 0 citations