Silent synapses represent a unique class of synaptic connections that are non-functional at rest but possess the potential to become functional, serving as a critical reservoir for neural plasticity. Their activation mechanisms not only challenge traditional models of synaptic maturation but also provide novel insights...
Yong-Li Li, Yong Liao, Shou-Yao Zhang et al.· Frontiers in Synaptic Neuros...· 0 citations
The eye is one of the most metabolically active organs, and mitochondria serve as the central hub for cellular energy metabolism by providing adenosine triphosphate through oxidative phosphorylation. Disruption of mitochondrial metabolism—including insufficient adenosine triphosphate synthesis, excessive production of...
Shou-Yao Zhang, Xiao-Chun Yang, Cheng-Gui Xu et al.· Frontiers in Cell and Develo...· 0 citations
Background Patients with depression exhibit significant gut microbiota dysbiosis; however, visualized studies into dysbiosis-related microbial signatures in depression remain limited. To identify characteristic differential genera in depressed individuals, this study adopted a knowledge graph–based visualization analys...
Cheng-Gui Xu, Shou-Yao Zhang, Yong Liao et al.· Frontiers in Microbiology· 0 citations
Cardiac senescence is not an isolated organ decline but a systemic consequence driven by pathological crosstalk between the heart and its peripheral metabolic organs. In this review, we discard the traditional organ–centric perspective and construct an integrated framework around multi-organ crosstalk axes, including t...
Shou-Yao Zhang, Cheng-Gui Xu, Yong-Li Song et al.· International Journal of Mol...· 0 citations
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