Author

Cheng Deng

2 papers indexed here

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Open access Aug 2026

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) poses an increasing threat to global public health. Currently approved drugs for MASLD, such as resmetirom and semaglutide, have demonstrated clinical efficacy. However, their use is associated with notable adverse effects, including serious gast...

Zong-Xi Li, Jing Song, Kai-Li Ma et al. · Advancement of science · 0 citations

Review Open access Oct 2026

Mosaic Loss of the Y Chromosome: Mechanisms and Diseases.

Mosaic loss of the Y chromosome (mLOY) is a male‑specific somatic loss of the Y chromosome that is predominantly observed in peripheral blood leukocytes, but can also be found in other tissue types. It represents one of the most common male-specific somatic mutations, particularly prevalent in aging individuals. Accumu...

Qi Zhang, Jiang Yu, X. Zhai et al. · Protein & Cell · 0 citations