Epicardial adipose tissue in obesity-related heart failure with preserved ejection fraction and atrial fibrillation: mechanisms, imaging, and therapeutic modulation
Obesity-related heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) often coexist, but the contribution of epicardial adipose tissue (EAT) to their overlap remains uncertain. EAT is anatomically contiguous with the myocardium and can undergo inflammatory, profibrotic and metabolic remode...