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Author

Chenxin Xu

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Open access Oct 2026

Antidepressant use and Parkinson's disease risk: Overall protective effect with drug‐specific variation

ABSTRACT Background Antidepressants can cause extrapyramidal side effects, but their impact on Parkinson's disease (PD) risk remains unclear. Aims We aimed to investigate the association between genetic liability to antidepressant use and PD. Methods We examined the causal effect of antidepressant use on PD using Mende...

Ancha Baranova, Hong-Bao Cao, Chen-Xin Xu et al. · 0 citations
Aug 2026

Association between antidepressant use and the risk of type 2 diabetes: a multi-stage Mendelian randomization study.

Genetic evidence suggesting medication-specific associations between antidepressant use liability and T2D susceptibility is provided, highlighting that the metabolic effects of individual antidepressants may vary, thus, warranting further studies to determine the clinical relevance of the findings.

Dongming Liu, Ancha Baranova, Chenxin Xu et al. · 0 citations

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