Author

Chen-Song Zhang

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Open access Jul 2026

Targeting HASPIN-mediated H3T3 phosphorylation disrupts an epigenetic-kinesin axis to suppress colorectal cancer mitotic progression.

The findings identify the HASPIN/H3T3ph-KDM5B-H3K4me3-KIF axis as a targetable antimitotic pathway and support therapeutic inhibition of HASPIN/H3T3ph as a potential strategy for CRC.

Tong Wu, Yaguang Zhang, Si-Cheng Liu et al. · Molecular Cancer · 0 citations