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OBJECTIVE Primary Sjögren's syndrome (pSS) is an autoimmune disease characterized by lymphocytic infiltration of exocrine glands and systemic immune dysregulation. Endoplasmic reticulum stress (ERS)-related transcription factor C/EBP homologous protein (CHOP) has been implicated in several autoimmune conditions, but it...
Findings identify CD55 as a marker of a distinct CD4+ T cell subset with altered functional and molecular characteristics and support its potential utility in the early diagnosis and differential diagnosis of RA.
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