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Chen-Liang Zhang

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Open access Aug 2026

Synergistic effects and molecular mechanisms of pirfenidone combined with EGFR-TKIs in non-small cell lung cancer

First evidence that PFD can restore drug sensitivity in OS-resistant cells and reversed acquired resistance to EGFR-TKIs is provided, offering valuable experimental support for its potential clinical application as an EGFR-TKI sensitizer and a therapeutic strategy to overcome resistance in targeted cancer therapies.

Pan Tang, Chen Huang, Feng-Mei Zhang et al. · 0 citations

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