Author

Chen-Jie Qiu

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Review Open access Oct 2026

TRIM22 in cancer: a context-dependent E3 ligase at the interface of interferon, p53, and tumor plasticity

TRIM22 is a TRIM family E3 ubiquitin ligase whose expression is strongly induced by interferons. For many years, it has been identified primarily as an antiviral effector, a role that remains well validated. A growing body of cancer-related work now forces us to expand that view considerably. Depending on tumor type, u...

Chen-Jie Qiu, Liang-Liang Dai · Frontiers in Cell and Develo... · 0 citations

Open access Oct 2026

Integrating Mendelian randomization with single-cell and spatial transcriptomics to investigate gut microbiota-associated genetic signals and molecular characteristics in prostate cancer

Prostate cancer (PRAD) represents one of the most prevalent malignancies among men globally. Accumulating evidence implicates gut microbiota dysbiosis in the initiation and progression of prostate cancer; however, the causal relationship and underlying molecular mechanisms remain incompletely elucidated. This study...

Chen-Jie Qiu, Hui-Lin Zhang, Zong-Min Du et al. · Frontiers in Cellular and In... · 0 citations