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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Chen Chen

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2 papers indexed here

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Review Open access Sep 2026

Post-translational acylation of proteins in colorectal cancer.

Accumulating preclinical evidence indicates that protein acylation, a functionally diverse class of post-translational modifications, is implicated in the regulation of protein stability, enzymatic activity, subcellular localization, molecular interactions, and gene transcription. In colorectal cancer (CRC), this modif...

Fan Xu, Shuo-Shuo Wang, Yun-Ting Le et al. · 0 citations
Open access Aug 2026

DYNAMIC CONFORMATIONS IN THE ACTIVATION OF PINK1 KINASE

Under mitochondrial stress, the mitochondrial kinase PINK1 is activated to phosphorylate ubiquitin, which in turn recruits the E3 ligase Parkin, thereby initiating clearance of damaged mitochondria. Dysregulation of the PINK1–Parkin signaling pathway is associated with early- onset autosomal recessive Parkinson’s disea...

Huiqin Xu, Xin-Yang Liu, Yan Jiang et al. · 0 citations

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