Sep 2026
Synonymous codon usage shapes ERα function through specialized translational programs during breast cancer progression.
It is shown that the transition of breast cancer cells from quiescent, differentiated states towards proliferative, less differentiated phenotypes, is accompanied by a systematic shift from G/C3- to A/U3-biased codon usage, identifying synonymous codon usage as a previously unrecognized mechanism linking translational...
Tamara Fernández-Calero, Raphaël Métivier, F. Percevault et al.
· Oncogene · 0 citations