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Author

Chao Zhang

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Aug 2026

The Five Sign: A hand posture suggesting insulo-opercular involvement in focal seizures.

OBJECTIVE The Five Sign is a previously underrecognized ictal hand posture characterized by full extension and spreading of the fingers. We aimed to determine its localizing value and underlying network basis in patients with drug-resistant focal epilepsy. METHODS We retrospectively analyzed 510 patients with drug-re...

Xiangzhi Lu, Weiyuan Luo, Zhengbo Zhao et al. · 0 citations
Open access Jul 2026

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

An integrative multiscale circuit‐level analysis in 250 patients with TLE delineates a multiscale circuit architecture underlying memory dysfunction and provides a biologically grounded basis for understanding cognitive vulnerability and may inform individualized risk assessment in epilepsy surgery.

Jiajie Mo, Qiwen Yuan, Pengfei Zhang et al. · 0 citations

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