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Author

Chao Zhang

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Open access Sep 2026

Naphthalimide-based andrographolide nanoplatform suppresses ccRCC via targeting the HIF-2α/VEGF signaling axis

Constitutive activation of hypoxia-inducible factor-2α (HIF-2α) is a central oncogenic driver in clear cell renal cell carcinoma (ccRCC). In this work, a naphthalimide-based multifunctional nanoplatform was developed as a drug delivery system for andrographolide (AG) to improve its therapeutic specificity. The resultin...

Jun Du, Chao Zhang, Li Zhang et al. · 0 citations

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