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Author

Chao Liu

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Aug 2026

Isopropoxate Exerts Neurotoxicity by Crossing the Blood-Brain Barrier and Mediating through Inflammation-Neurotransmitter Signaling Pathways.

Isopropoxate (IPPO), an emerging imidazole ester-type new psychoactive substance, poses potential risks to public health and the environment, yet its neurotoxic mechanisms remain poorly understood. In this study, 8-week-old C57BL/6J mice were used to evaluate the effects of IPPO on the blood-brain barrier (BBB), oxidat...

R. Cao, Zi-En Chen, Ji-Hong Cai et al. · 0 citations
Open access Aug 2026

A Multitask Large Reasoning Model for Molecular Science

A task-adaptive large reasoning model that integrates chemical knowledge through a synergistic multispecialist architecture, chain-of-thought supervision, and molecule-informed reinforcement learning is presented, demonstrating a versatile multitask framework for knowledge-guided molecular reasoning and design.

Pengfei Liu, Shuang Ge, Xiaobo Wang et al. · 0 citations

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