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Author

Chao Lin

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Open access Sep 2026

Identification of benzoxazine scaffold derivatives as novel CDK4 inhibitors for the treatment of cancer

Mechanistic investigations revealed that 8j induces G1 phase cell cycle arrest and promotes apoptosis, which was corroborated by the observed concentration-dependent downregulation of key cell cycle regulators, including CDK4 and cyclin D1.

Chao Lin, Shao-Feng Sun, Hua-Teng Zhang et al. · 0 citations

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