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Chao-Hui Gu

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Open access Sep 2026

Multimodal AI and single-cell transcriptomics integrate to construct a histopathological prognostic model for bladder cancer, revealing the RTN3-glycolysis axis in chemoresistance

The findings establish the RTN3/JAK2/STAT3/glycolytic metabolic reprogramming axis as a critical mechanism of gemcitabine resistance, highlighting RTN3 as a promising therapeutic target for overcoming chemoresistance in bladder cancer.

Shun-Li Yu, Ying-Jian Wang, Da-Peng Feng et al. · 0 citations

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