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Chang-Zhou Yan

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2026

Validating AIEgen-Labeled Nanoplastics as Silent Tracers to Elucidate Surface Charge-Dependent Transcriptomic Divergence in Hepatotoxicity

As emerging contaminants, micro/nanoplastics (MNPs) are widely present in the environment. However, in toxicity studies of MNPs, traditional fluorescence labeling suffers from photobleaching issues and additional toxicity, making it difficult...

Jing Zhu, Mei-Ping Tian, Qing-Yu Huang et al. · 0 citations
Open access Jul 2026

Spatially resolved hepatic lipid metabolism perturbation and gut microbiota dysbiosis induced by a novel PFOA alternative in zebrafish (Danio rerio).

Together, the microbiome shift toward phospholipid remodeling-associated taxa and the spatially resolved hepatic perturbation of specific phospholipids provide convergent evidence that targeted phospholipid metabolic remodeling within tissue microregions may underlie HFPO-TeA-induced metabolic toxicity.

Qiu-Yue Shi, Jia-Cong Chen, Chuan-Sheng Zhang et al. · 0 citations

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