Open access
Jul 2026
NSUN2-mediated m5C modification of E2F1 promotes lung adenocarcinoma progression via the RAD54L signaling axis.
This work identifies a hierarchical signaling axis driven by the RNA methyltransferase NSUN2 that fuels LUAD progression and establishes the NSUN2-E2F1-RAD54L axis as a critical driver of LUAD and a promising target for therapeutic intervention.
Yue Li, Chen Chen, Hailin Liu et al.
· Respiratory Research · 0 citations