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Open access Sep 2026

CXCL3 Antagonism Reverses Systemic Antitumor Immune Memory Impairment Associated With High Tumor Burden and Sensitizes Anti‐PD‐1 Therapy

ABSTRACT High tumor burden is associated with poorer immunotherapy responses compared to low burden, yet the systemic mechanisms driving this impairment and strategies to reverse it remain unclear. We demonstrate that tumors with higher malignancy or stages exert a more pronounced suppression on systemic antitumor immu...

Ji Wang, Xin-Yu Tang, Ze-Ju Li et al. · 0 citations
Review Open access Sep 2026

Adipose-derived microvascular fragments: Functional microtissue units driving vascular integration and multidimensional tissue regeneration

Rapid and stable vascularization remains one of the major challenges in regenerative medicine and tissue engineering. Adipose-derived microvascular fragments (ad-MVFs) have emerged as a promising vascularization strategy because they preserve intact microvascular architecture while retaining endothelial cells, perivasc...

Yu-Yin Hou, Wen-Xin Yu, Zi-Run Yang et al. · 0 citations

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