Author

Chang-Nian Li

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Open access Sep 2026

Berberine attenuates diabetic kidney injury via FOXO1/SP1-associated regulation of renal SGLT-2 expression

Berberine (BBR), a plant-derived isoquinoline alkaloid, has been reported to exert anti-hyperglycemic and renoprotective effects. However, the mechanism by which BBR regulates renal glucose transport under diabetic conditions remains unclear. Sodium-glucose cotransporter-2 (SGLT-2), mainly expressed in renal proximal t...

Jing-Jing Pan, Xin-He Wang, Xin-Yuan Han et al. · Chinese Medicine · 0 citations

Review Open access Sep 2026

Anti-CD38 monoclonal antibodies in multiple myeloma and beyond: immunotherapeutic mechanisms, evidence maturity, and clinical positioning

This Review critically evaluates CD38 biology, Fc-mediated immune-effector mechanisms, immune remodeling, clinical evidence, resistance, safety, laboratory interferences, biomarker evidence, and clinical positioning of anti-CD38 antibodies, with multiple myeloma as the central reference disease.

Li-Ming Yu, Chang-Nian Li, Da-Dong Guo et al. · Frontiers in Immunology · 0 citations

Open access Sep 2026

Other primary malignancies are associated with inferior survival in multiple myeloma: a single-center matched retrospective cohort study

Lung and prostate cancers were the most common OPMs in this cohort, highlighting the need for heightened clinical attention to these malignancies in patients with MM.

Chang-Nian Li, Ya-Ru Wang, Lu-Lu Li et al. · Frontiers in Oncology · 0 citations