Solute transport through the glomerular filtration barrier: the podocyte slit diaphragms' role in maintaining glomerular basement membrane integrity and podocyte-to-endothelial crosstalk.
A two-dimensional computational solute transport model is developed incorporating two cross-sectional GFB geometries that suggest the structural organization of the GFB, particularly the slit diaphragm, enables solute distribution and directional transport, and therefore provides insight into GFB maintenance and pathology.
A. Azadi, Chang-Joon Lee, David W. Smith et al.
· Tissue Barriers · 0 citations