Chang-Hao He

Ferroptosis–immune crosstalk in ionizing radiation–induced testicular injury: mechanisms and therapeutic opportunities

Accumulating evidence suggests that ferroptosis—an iron–dependent, lipid peroxidation–driven form of regulated cell death—may contribute substantially to ionizing radiation (IR)–induced testicular injury. In this review, we develop a hypothesis–generating framework for ferroptosis–immune crosstalk in the testis. Within...