Bufalin Targets CENPA-modulated Glycolysis via PI3K/AKT in Hepatocellular Carcinoma: A Bioinformatics, In Vitro and Preliminary In Vivo Evidence.
BACKGROUND Hepatocellular carcinoma (HCC) remains a substantial therapeutic challenge because of its high recurrence rate and resistance to conventional therapies, necessitating the exploration of novel approaches. A crucial aspect of cancer metabolism is the Warburg effect, which promotes tumor progression by increasi...