Chang-Bin Chen

Fungal Phosphatase-Dependent Induction of Host Cell Pyroptosis by Candidalysin

Fungal infections pose a major public health threat and can cause host cell damage through diverse forms of regulated cell death. However, our understanding of how fungal pathogens interact with host to elicit pyroptosis remains in its infancy. Here, we show that candidalysin, the cytolytic peptide toxin of Candida a...