Impact of non-enteric-coated pancreatic enzyme replacement therapy (NEPERT) on pain in patients with chronic pancreatitis: a double-blind, parallel-group, placebo-controlled, randomised trial.
BACKGROUND Pain in chronic pancreatitis (CP) is multifactorial. Efficacy of pancreatic enzyme replacement therapy (PERT) for pain remains uncertain. OBJECTIVE To assess the effect of non-enteric-coated PERT (NEPERT) on pain in CP. DESIGN In this 24-week, double-blind, placebo-controlled, randomised trial, we enroll...