Monkeypox, caused by MPXV, has become a global public health concern; however, the T-cell immunity against MPXV following smallpox vaccination remains unclear. In this study, we screened the immunogenicity of 21 predicted MPXV epitopes and compared immune responses between young and elderly groups. Two immunogenic CD8⁺...
Yu-Juan Du, Zong-Mian Yang, Yin-Ying Xiao et al.· bioRxiv· 0 citations
This review systematically elaborates on the pathological characteristics and molecular mechanisms of aging, analyzes the application paradigms of multi-omics in biomarker screening, mechanism elucidation, and high-throughput screening, and discusses the core value and technical bottlenecks of AI in target prediction,...
Li-Juan Gao, Yong-Sheng Qin, Yudai Xu et al.· Frontiers in Aging· 0 citations
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