Chan-seok Jeong

AcrSeek: Metric Learning with Hybrid Negative Mining for Anti-CRISPR Protein Detection under Extreme Class Imbalance.

A metric-learning framework that trains a projection head over a frozen protein language model (PLM) encoder with hybrid negative mining with hybrid negative mining under a joint triplet–focal objective that remains structurally robust under extreme class imbalance and may also serve other protein-function detection pr...