Author

Chad M. Aldridge

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Open access Aug 2026

Genomic insights into stroke recovery: cross-phenotype associations

Abstract Stroke is a major cause of long-term disability with variable recovery. While clinical factors such as initial severity play a role, genetic factors are increasingly recognized as important contributors to stroke recovery. Genotype studies are generally focused on a single post-stroke behavioural domain, but s...

Chad M. Aldridge, R. Braun, L. Parodi et al. · Brain Communications · 0 citations

Open access Sep 2026

Evaluation of functional annotation-informed and ancestry-specific polygenic risk scores for ischemic stroke

Introduction Ischemic stroke (IS) is a leading cause of morbidity and mortality, and predicting events remains challenging. Polygenic risk scores (PRSs) aggregate genetic variants, but performance varies across ancestries and remains modest, particularly in non-European populations. Methods We compared Bayesian PRS met...

N. Armstrong, V. Srinivasasainagendra, Amit Patki et al. · Frontiers in Bioinformatics · 0 citations