Open access
Sep 2026
Transposon Vectors Enable Accelerated Development of Cellular Assay Platforms for the Identification and Characterization of Anti-Viral Small-Molecule Cell-Entry Inhibitors and Neutralizing Antibodies
Background/Objectives: Screening for neutralizing antibodies (nAbs) or antiviral small-molecule inhibitors (SMIs) using live virus is laborious and often confined to higher biosafety levels, thus restricting accessibility. The use of murine leukemia virus (MLV)-derived pseudotype vector particles displaying spike or en...
Mona Pißarreck, Kristina Katsoutas, Celina Lea Kinder et al.
· Biomedicines · 0 citations