Author

Cédric Blanpain

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Aug 2026

Simultaneous single-cell profiling of chromatin, transcriptome and surface markers with OneCell CUT&Tag captures epigenomic reprogramming.

This approach uncovers epigenomic priming of basal cells in the mammary gland and captures the dynamics of basal-to-luminal transdifferentiation, suggesting that epigenomic and transcriptional remodeling do not occur in complete synchrony during cell-fate conversion.

Anna Schwager, Eve Moutaux, Adeline Durand et al. · Nature Biotechnology · 0 citations

Open access Jul 2026

Single cell multiomics unravel the transcription networks controlling the different EMT tumor states

The authors use single-cell multiomics and CRISPR/Cas9-mediated loss-of-function studies to identify key transcription factors controlling EMT states and metastasis and defines the transcriptional and chromatin landscape controlling EMT progression in mouse skin SCC.

Andrea Pérez-González, Gabriel Windels, Kévin Bévant et al. · Nature Communications · 1 citation