Catherine J. Merrick

Lactylated histones mark virulence gene families in the malaria parasite Plasmodium falciparum

Epigenetic pathways have many important roles controlling virulence in human malaria parasites. Histone acetylation and methylation have been closely studied in this context but the novel epigenetic mark of lactylation has not yet been examined. Here, for the first time, we profiled lactyl-histone marks across the P. f...