Catherine G. Triandafillou

Single-cell spatial mapping reveals reproducible cell type organization and spatially dependent gene expression in gastruloids

Gastruloids are stem-cell-based models that recapitulate key aspects of mammalian gastrulation, including the formation of an anterior-posterior axis. However, we do not have detailed spatial information about gene expression and cell type organization, particularly at the level of individual gastruloids. Here, we repo...