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Author

Carrie Jonak

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Open access Sep 2026

Atlas-Based Electrical Source Imaging for Mouse EEG: Application to an Fmr1 Knockout Model.

Electrical source imaging (ESI) reconstructs where in the brain a scalp EEG signal arises. It is routine in humans but unestablished in the mouse, whose brain is some 3,000 times smaller where it is not obvious that a sparse array can separate one region from another. We built an atlas-based ESI pipeline for 30-channel...

Alex D. Edmondson, Andrew D. Gaulden, Richard K. Lacher et al. · 0 citations
Sep 2026

A cell type-specific switch in GluN2D NMDA receptors drives cortical circuit hyperexcitability and sensory-driven cortical synchronization deficits in a Fragile X Syndrome model.

BACKGROUND Altered sensory processing and sensitivity are prevalent in Fragile X Syndrome (FXS) and may be mediated by dysfunction of cortical circuits. Evidence from individuals with FXS and/or the FXS mouse model, Fmr1 KO, indicates hyperexcitability of sensory cortical circuits, deficits in sensory-driven circuit sy...

Aleya Shedd, Carrie Jonak, Leo Chan et al. · 1 citation

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