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Carole A. Bewley

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Review Open access Aug 2026

Engineering Protein-Based HIV Entry Inhibitors: Advances, Challenges, and Translational Strategies

This review highlights promising protein-based HIV entry inhibitors that have demonstrated efficacy in preclinical studies, and discusses ongoing efforts to optimize their valency, avidity, specificity, serum half-life, effector functions, and production platforms to improve their therapeutic potential and economic feasibility.

Rashmi Kumariya, Carole A. Bewley · Biomolecules · 0 citations