Carlos A. Zarate

Treatments for Individuals with Suicidal Thoughts: Use, Indications, and Helpfulness

Background: Although millions of adults seriously consider suicide each year, clinical trials often exclude individuals experiencing suicidal ideation (SI). This analysis sought to describe the use of a range of psychiatric treatment modalities in individuals with mood disorders with and without a history of suicide at...

Plasma copeptin is coupled to resting-state frontoinsular-subgenual alpha dynamics in major depression with comorbid post-traumatic stress disorder

Background Hypothalamic-pituitary-adrenal axis dysregulation is implicated in depression and post-traumatic stress disorder (PTSD), but stress-related neuroendocrine mechanisms that distinguish their comorbid presentation remain poorly understood. Prior work in the broader parent cohort found lower levels of plasma cop...

Modulation of GABA and glutamate by ketamine in depression: A systematic review and meta-analysis of magnetic resonance spectroscopy studies.