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Carel Pretorius

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#protein folding Open access Oct 2026

Conformation‐Selective Binding Domains of Intramolecular Chemically Induced Protein Dimerisation Systems

ABSTRACT Chemically induced protein dimerisation (CID) is a widely used approach for detecting and actuating small‐molecule‐protein interactions. Here, we demonstrate that CID systems can be used as building blocks for higher‐order ligand‐controlled protein systems. To this end, we converted classical FK506‐ and cyclos...

Zhenling Cui, Zhong Guo, Yi Jin Liew et al. · 0 citations

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