Multiscale neurobiological architecture of functional synchronization abnormalities in primary angle-closure glaucoma: an imaging-transcriptomics study.
This study provides multidimensional evidence that PACG-induced functional synchronization alterations are tightly constrained by underlying transcriptomic gradients, glial-vascular networks, and neurochemical architectures, reinforcing the conceptualization of PACG as a systemic central neurodegenerative disease.