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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Camilo Fernández Bravo

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Review Open access Sep 2026

Beyond the Failing Heart: Deciphering the Multisystem Biology ofHeart Failure Through Remodeling, Immunometabolism, Fibrosis,and Interorgan Crosstalk

This comprehensive review and quantitative meta-analysis systematically decipher the multisystem biology of HF across four interconnected pillars: structural and subcellular myocardial remodeling, immunometabolic reprogramming, extracellular matrix (ECM) dynamics and fibrosis, and interorgan crosstalk.

Camilo Fernández Bravo · 0 citations

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