Open access
Aug 2026
Neuronal expression of bromodomain proteins alters neuronal health and peripheral protein homeostasis to promote longevity
It is shown that the neuronal expression of the chromatin reader BET-1 promotes longevity and resilience in C. elegans through signaling mechanisms involving master transcription factors HSF-1 and DAF-16 and neurotransmitter UNC-13.
Naibedya Dutta, Daniel Hicks, Edgar Esparza et al.
· Genes & Development · 0 citations