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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Cai-Hong Sun

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Aug 2026

Integrated network pharmacology and lipidomics provide insights into potential mechanisms underlying the effects of cannabidiol in a rat model of autism.

BACKGROUND Cannabidiol (CBD) has shown potential benefits in managing symptoms associated with autism spectrum disorder (ASD), although its underlying mechanisms of action remain unclear. This study investigated whether CBD improves ASD-like behavior in association with changes in lipid metabolic disturbances and apopt...

Hao-Ran Wang, Yu-Ting Zhang, Yi Jiang et al. · 0 citations
Open access Sep 2026

Genetic and pharmacological evidence linking CB1R signaling to hippocampal GABAergic dysfunction in ASD mouse model

Autism spectrum disorder (ASD) is a neurodevelopmental disorder increasingly linked to disrupted GABAergic inhibition and altered excitatory-inhibitory balance. Cannabinoid receptor 1 (CB1R), enriched on GABAergic interneurons, modulates inhibitory tone. Whether CB1R dysfunction in GABAergic neurons contributes to ASD-...

Jing-Yi Hu, Hao-Ran Wang, Jun-Yu Ren et al. · 0 citations
Open access Aug 2026

A case-control analysis: changes in gut microbiota composition in children with autism spectrum disorder

Children with ASD exhibited significant differences in gut microbiota composition compared with TD children, characterized by a functional compositional imbalance-systematic depletion of butyrate-producing bacteria and Bifidobacterium spp.

Le Kang, Lin-Lin Fan, Ying Tian et al. · 0 citations

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