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Open access Jul 2026

Regulation of Th17 Cell Survival by the CREB/CRTC2—GPR65 Axis: Mechanistic and Translational Insights 2249331

Th17 cells are critical mediators of autoimmune inflammation, but the molecular pathways that sustain their survival and metabolic function remain incompletely defined. Our prior studies identified the CREB/CRTC2 transcriptional pathway as a key regulator of Th17 differentiation. Transcriptomic analyses revealed...

Jeniffer B. Hernandez, Helena Wollam, C. Ybanez · 0 citations

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