Author

C. Werts

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Open access Oct 2026

Archaeal cell envelopes selectively activate innate immunity through TLR2 in contrasts with multi-receptor bacterial sensing

The cell envelope of bacteria and fungi is a major source of microbial-associated molecular patterns (MAMPs), which are recognised by multiple host pattern recognition receptors (PRRs) such as TLRs and NODs. The key role of this recognition in protecting against infection and regulating diverse physiological processes...

C. Martin-Gallausiaux, Charles Grosjean, B. Baker et al. · bioRxiv · 0 citations

Open access Sep 2026

Primary human dermal fibroblasts selectively sense LPS, poly I:C and ADP heptose and initiate immune response mostly through chemokine secretion.

Fibroblasts are considered structural cells that maintain tissue homeostasis and facilitate repair. They also participate in innate immunity, although their pattern recognition capabilities remain incompletely characterized. Here, we systematically assessed the innate immune responses of commercially available primary...

J. Klein, Christophe Gallard, B. David-Watine et al. · Innate Immunity · 0 citations