Ficus carica fruit extract induces mitochondria-mediated apoptosis in C6 glial cells.
BACKGROUND Ficus carica fruit extract (FCFE) was evaluated for its cytotoxic and apoptotic effects against C6 glial cells. FCFE has been traditionally used for the treatment of neurodegenerative diseases. METHODS In this study, cytotoxicity, reactive oxygen species (ROS) generation, and the mitochondrial-mediated apo...