Author

C. Shan

3 papers indexed here

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Open access Sep 2026

Transcriptomics-based analysis of muscle injury mechanism mediated by inflammatory imbalance in the Duchenne muscular dystrophy muscle microenvironment

Background Duchenne muscular dystrophy (DMD) is a hereditary neuromuscular disease characterized by progressive myofiber injury, chronic inflammatory response, and persistent fibrotic remodeling, for which no universal clinical treatment is currently available. The inflammatory-fibrotic microenvironment is regarded as...

C. Shan, Yu Li, Nan Li et al. · Frontiers in Neurology · 0 citations

Oct 2026

Galectin-3 accelerates the progression of cerebral infarction by regulating the ERK/ROS/BRD4-mediated P2X7R/MerTK balance in microglia.

This study demonstrates that Galectin-3 (Gal3) exacerbates cerebral infarction progression by modulating the P2X7R/MerTK equilibrium in microglia via the ERK/BRD4/HIF1α signaling axis, with reactive oxygen species (ROS) serving as a potential intermediate mediator linking ERK activation to BRD4 upregulation based on pr...

C. Shan, Qiao-Zhao Bing, Gang Qiu et al. · Biochemical and Biophysical... · 0 citations

Sep 2026

A Quantitative Nomogram Integrating IVIM-derived True Diffusion Coefficient and PSAD for Predicting Clinically Significant Prostate Cancer: Comparison With PI-RADS-based Assessment.

The PSAD + D nomogram achieves diagnostic performance comparable to PI-RADS + PSAD for predicting csPCa while eliminating reader dependency through objective, highly reproducible parameters (intraclass correlation coefficients).

Xiao-Bo Wang, Yi-Ze Li, Zi-Qi Chen et al. · Academic Radiology · 0 citations