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Author

C. Rawson

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Review Open access Aug 2026

Diagnostic evaluation of suspected aneurysmal subarachnoid hemorrhage after negative CT: risk-stratified use of lumbar puncture and CT angiography

Aneurysmal subarachnoid hemorrhage (SAH) is a neurologic emergency in which delayed or missed diagnosis can result in substantial morbidity and mortality. In patients who present with clinical features concerning for SAH but have a normal or non-diagnostic non-contrast head computed tomography (CT), the optimal next di...

C. Rawson, Yashieta Somani, M. Karsy et al. · 0 citations
Review Open access Oct 2026

The Tumor Neuroimmune Niche: A Unifying Framework for Cancer Progression and Its Neuropsychiatric Burden.

BACKGROUND Cancer has traditionally been framed as a cell-intrinsic genetic disease and, more recently, as a disorder of the tumor microenvironment (TME). An emerging third view reframes malignancy as a systems-level neuroimmune disorder, in which neurons, glia, immune cells, and tumor cells form a continuously communi...

Agastya Mittal, C. Rawson, Jaime Tellez et al. · 0 citations
Sep 2026

Global Burden of Pediatric Stroke (1990-2023): A Shift From Mortality Toward Disability.

BACKGROUND Pediatric stroke is a significant cause of long-term disability worldwide, with outcomes influenced by age, stroke subtype, and access to care. Our objective was to define the global burden of pediatric stroke by its impact on mortality and disability. METHODS The Global Burden of Disease study uses advanc...

C. Rawson, Lisa M. Pabst, Karol P. Budohoski et al. · 0 citations
Review Open access Aug 2026

Optimization of Focused Ultrasound-Mediated Blood–Brain Barrier Opening for CNS Therapeutic Delivery: Mechanistic Insights, Technical Parameters, and Clinical Translation

BBB microdisruption, particularly through FUS with microbubbles, represents a transformative platform for central nervous system gene therapy, and continued research is needed to standardize treatment protocols, characterize long-term safety, and facilitate broader clinical translation.

M. Rashad, Agastya Mittal, Srivardhan Chirasani et al. · 0 citations
Review Open access Aug 2026

Brain-Tropic Metastasis: Mechanistic Checkpoints Governing Cerebral Colonization.

The strongest mechanistic support for cerebral organotropism was identified in breast cancer, oncogene-driven non-small cell lung cancer, and melanoma, while the biological pathways underlying brain metastasis in renal cell carcinoma and colorectal cancer remain comparatively less defined.

Henry Freeman, C. Rawson, Denise Baloi et al. · 0 citations

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