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C. Pierpaoli

1 paper indexed here

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Open access Sep 2026

Evaluating Precision and Responsiveness of MRI-derived Brain Volumetric and Clinical Outcome Measures in CLN3 Disease

Background and Objective: For their acceptance as endpoints in clinical trials, biomarkers and clinical outcome assessment (COA) measures should show reliability by being reproducible (precise) and responsive to change. We evaluated precision and responsiveness of MRI-derived brain volume metrics and various COAs in ce...

R. Hafiz, C. Farmer, L. Joseph et al. · 0 citations

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