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Review Open access Sep 2026

Circular RNAs: from transcriptional noise to engineered therapeutics

Circular RNAs (circRNAs) are single stranded, closed, primarily non-coding RNA circles that have risen to the forefront of the non-coding RNA field. Studies from recent years have shown that circRNAs are produced from endogenous, non-canonical RNA splicing mechanisms, demonstrate specific cellular localizations, regula...

Aaron C. Chack, C. Pecot · 0 citations

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